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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Probable G-protein coupled receptor 174
Species	Homo sapiens (Human)
Gene	GPR174
Synonym	FKSG79 GPR174
Disease	N/A
Length	333
Amino acid sequence	MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC
UniProt	Q9BXC1
Protein Data Bank	N/A
GPCR-HGmod model	Q9BXC1
3D structure model	This predicted structure model is from GPCR-EXP Q9BXC1.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562167
IUPHAR	145
DrugBank	N/A

Ligand

Name	CHEMBL3577145
Molecular formula	C22H44NO9P
IUPAC name	(2S)-2-amino-3-[[(2R)-3-hexadecanoyloxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
Molecular weight	497.566
Hydrogen bond acceptor	10
Hydrogen bond donor	4
XlogP	2.0
Synonyms	ZINC85604003 LMGP03050002 PS(16:0/0:0) LPS(16:0) 1-hexadecanoyl-sn-glycero-3-phosphoserine SCHEMBL13863416 BDBM50096353 L-Serine, 2-hydroxy-3-[(1-oxohexadecyl)oxy]propyl hydrogen phosphate (ester), sodium salt, (R)- Palmitoyllysophosphatidylserine 1-palmitoyl-sn-glycero-3-phospho-l-serine [ Show all ]
Inchi Key	XIVOBOJQPNEUSC-UXHICEINSA-N
Inchi ID	InChI=1S/C22H44NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-21(25)30-16-19(24)17-31-33(28,29)32-18-20(23)22(26)27/h19-20,24H,2-18,23H2,1H3,(H,26,27)(H,28,29)/t19-,20+/m1/s1
PubChem CID	9547100
ChEMBL	CHEMBL3577145
IUPHAR	N/A
BindingDB	50096353
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	537.0 nM	PMID25970039	BindingDB
EC50	537.03 nM	PMID25970039	ChEMBL
EC50	540.0 nM	PMID25970039	BindingDB,ChEMBL

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