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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Neuropeptide S receptor
Species	Homo sapiens (Human)
Gene	NPSR1
Synonym	G-protein coupled receptor for asthma susceptibility vasopressin receptor-related receptor 1 G protein-coupled receptor 154 PGR14 NPS receptor G-protein coupled receptor 154 GPR154 G-protein coupled receptor PGR14 VRR1 [ Show all ]
Disease	Neurological disease
Length	371
Amino acid sequence	MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI
UniProt	Q6W5P4
Protein Data Bank	N/A
GPCR-HGmod model	Q6W5P4
3D structure model	This predicted structure model is from GPCR-EXP Q6W5P4.
BioLiP	N/A
Therapeutic Target Database	T20958
ChEMBL	CHEMBL5162
IUPHAR	302
DrugBank	BE0000948

Ligand

Name	N-(3,5-dimethylphenyl)cyclopentanecarboxamide
Molecular formula	C14H19NO
IUPAC name	N-(3,5-dimethylphenyl)cyclopentanecarboxamide
Molecular weight	217.312
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	3.4
Synonyms	HMS2459A19 STK483146 AKOS001127154 MolPort-002-243-470 CHEMBL1391494 SMR000064983 544457-48-9 MCULE-6267599895 Z30889798 AN-652/42917791 HMS1744M12 ST50928372 AC1LHH6B MLS000054675 ZINC365158 N-(3,5-dimethylphenyl)cyclopentylcarboxamide [ Show all ]
Inchi Key	AATFGQMTHPPNTJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H19NO/c1-10-7-11(2)9-13(8-10)15-14(16)12-5-3-4-6-12/h7-9,12H,3-6H2,1-2H3,(H,15,16)
PubChem CID	837844
ChEMBL	CHEMBL1391494
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Potency	12589.3 nM	PubChem BioAssay data set	ChEMBL

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