Detailed GPCR-I-TASSER Statistics for Q6W5P4

Submitted Sequence

>sp|Q6W5P4|NPSR1_HUMAN
MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
VFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLV
CRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIP
TLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK
SKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFN
LLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERH
EMQILSKPEFI

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |           
Sequence MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI
Prediction CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCSSSSSSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 98998999888888888888898788887777766666555553257999999999999999999999999999747888703999999999999999998799999999488363245885299999999999999999997011412135687411388999998999999999999999987759936990799861897538999999999999999999999999999999976258654321222323222310142788988899999999999999998999999999997355464167999999999999999899999998199999999998466567888888877778757887789

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |           
Sequence MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI
Prediction 74443343313343333313122232233233343343343332222020000211110021013000000000013323010000010003001010000010100000143220120001003001000000000000000130020001002312133100000000010000000000000002426643212113012630210000000121133102101300020001013334335444544454443444444323301100000000000000000221000000100131243412100100001000200021000000004300410240032344343465344443533345624

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |           
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCSSSSSSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI
14n6hA 0.18 0.20 0.80 2.75Download ------------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTMKTATNIYIFNLALADALATSTLPFQSAKYLM--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPR-DGAVVCMLQFPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS----------------KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------
25gliA 0.20 0.23 0.85 3.88Download ---------------------------------SPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLYIIYKNKMRNGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKLRICLLHPVQKFYATAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKNIFEMLRIDEGGGSGGDEAEKLNDHLKQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDSFLLVLDYIGINMASLNSCANPIALYLVSKRFKNAFKSALCC------------------------
34n6hA 0.18 0.20 0.80 3.65Download ------------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYKMKTATNIYIFNLALADALATST-LPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-AVVCMLQFPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSK----------------EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------
44djh 0.21 0.23 0.80 1.54Download --------------------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRTKMKTATNIYIFNLALADALVTT-TMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDTPLKAKIINICIWLLSSSVGISAIVLGGTKVRDVDVIECSLQFPDDDYWLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNIFDEGLNGKRNQTPAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA--A---LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP------------------------
54rnb 0.21 0.22 0.81 1.16Download --------------------------------------------PKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPS----TAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQGIDCSFWNKKRQSRSDRAMSFSKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMHDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC------------------------
64n6hA 0.18 0.20 0.79 3.01Download ---------------------------------------ARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTMKTATNIYIFNLALADALA-TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-AVVCMLQFPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS----------------KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------
73uon 0.21 0.23 0.79 1.72Download ------------------------------------------------VVFIVLVAGSLSLVTIIGNILVMVSIKVNHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVVEDGECYIQFFS---NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEMLRIDERNGVRTGTWDAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCI---PNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM-------------------------
84ea3A 0.20 0.19 0.74 4.06Download --------------------------------------------PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRTKMKTATNIYIFNLALADTLVLLT-LPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPT-----SSKAQAVNVAIWALASVVGVPVAIMGS-AQVEDEEIECLVETPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGS----------------REKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFR-----------------------------
94n6hA 0.18 0.20 0.80 2.82Download ------------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTMKTATNIYIFNLALADALATSTLPFQSAKYLM--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPR-DGAVVCMLQFPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS----------------KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------
105c1mA 0.19 0.19 0.78 3.36Download ---------------------------------GSHSLPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYKMKTATNIYIFNLALADALAT-STLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYR-QGSIDCTLTFSHWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGS----------------KEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.22 (Read more about C-score)
  • Estimated TM-score = 0.68±0.12
  • Estimated RMSD = 7.1±4.2Å

  • Download Model 2
  • C-score = -1.15

  • Download Model 3
  • C-score = -0.19

  • Download Model 4
  • C-score = -2.41

  • Download Model 5
  • C-score = -1.38


    • [Click on Q6W5P4_results.tar.bz2 to download the tarball file including all modeling results listed on this page]