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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Homo sapiens (Human)
Gene	DRD1
Synonym	D1 receptor D1A DADR Gpcr15 dopamine D1 receptor Dopamine-1A receptor [ Show all ]
Disease	Unspecified Hypertension Pain Parkinson's disease Psychiatric disorder Psychotic disorders Schizophrenia Substance dependence Type 2 diabetes Excessive bleeding following childbirth and spontaneous or elective abortion Cocaine addiction Dementia Cognitive disorders [ Show all ]
Length	446
Amino acid sequence	MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P21728
Protein Data Bank	N/A
GPCR-HGmod model	P21728
3D structure model	This predicted structure model is from GPCR-EXP P21728.
BioLiP	N/A
Therapeutic Target Database	T22118
ChEMBL	CHEMBL2056
IUPHAR	214
DrugBank	BE0000020

Ligand

Name	7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
Molecular formula	C22H40O2
IUPAC name	(5Z,8Z)-7,7-dimethylicosa-5,8-dienoic acid
Molecular weight	336.56
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	8.5
Synonyms	AGKRHAILCPYNFH-DUQSFWPASA-N DEDA LMFA01020253 NCGC00015371-05 NCGC00261147-01 7,7-Dimethyl-eda BSPBio_001459 HMS1791I21 MFCD00133010 NCGC00093876-01 SR-01000075833-1 (5Z,8Z)-7,7-Dimethylicosa-5,8-dienoic acid 89560-01-0 CHEMBL1323529 HMS3402I21 NCGC00015371-03 NCGC00093876-04 5,8-Eicosadienoic acid, 7,7-dimethyl-, (Z,Z)- 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid, >=95% BML3-B09 EU-0100462 Lopac-D-8008 NCGC00015371-06 SCHEMBL1319566 7,7-Dimethyl-eicosadienoic acid CCG-204554 HMS1989I21 NCGC00015371-01 NCGC00093876-02 Tox21_500462 (Z,Z)-7,7-dimethyl-5,8-eicosadienoic acid AC1NSMI1 D 8008 IDI1_033929 NCGC00015371-04 NCGC00093876-05 7,7-dimethyl-(5z,8z)-eicosa-dienoic acid 7,7-dimethyl-5Z,8Z-eicosadienoic acid BRD-K65207153-001-02-9 HMS1361I21 LP00462 NCGC00015371-07 SR-01000075833 7,7-dimethyleicosadienoic acid HMS3261M06 NCGC00015371-02 NCGC00093876-03 ZINC8034913 5,8-Eicosadienoic acid, 7,7-dimethyl-, (5Z,8Z)- [ Show all ]
Inchi Key	AGKRHAILCPYNFH-DUQSFWPASA-N
Inchi ID	InChI=1S/C22H40O2/c1-4-5-6-7-8-9-10-11-12-13-16-19-22(2,3)20-17-14-15-18-21(23)24/h16-17,19-20H,4-15,18H2,1-3H3,(H,23,24)/b19-16-,20-17-
PubChem CID	5312331
ChEMBL	CHEMBL1323529
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Potency	2909.1 nM	PubChem BioAssay data set	ChEMBL

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