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Name | D(2) dopamine receptor |
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Species | Mus musculus (Mouse) |
Gene | Drd2 |
Synonym | D2 receptor D2(415) and D2(444) D2A and D2B D2R dopamine D2 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 444 |
Amino acid sequence | MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC |
UniProt | P61168 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3427 |
IUPHAR | 215 |
DrugBank | N/A |
Name | CHEMBL136701 |
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Molecular formula | C22H30FNO2 |
IUPAC name | 2-(4-fluorophenyl)-1-[1-(3-phenylpropyl)piperidin-4-yl]ethanol;hydrate |
Molecular weight | 359.485 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | None |
Synonyms | N/A |
Inchi Key | CSGALTMQYNFREC-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C22H28FNO.H2O/c23-21-10-8-19(9-11-21)17-22(25)20-12-15-24(16-13-20)14-4-7-18-5-2-1-3-6-18;/h1-3,5-6,8-11,20,22,25H,4,7,12-17H2;1H2 |
PubChem CID | 44357683 |
ChEMBL | CHEMBL136701 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 1700.0 nM | PMID1360026 | ChEMBL |
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