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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 1
Species	Mus musculus (Mouse)
Gene	Cnr1
Synonym	SKR6R Neuronal cannabinoid receptor Central cannabinoid receptor CB1R CB1 receptor CB1 CB-R Cann7 Cann6 Brain-type cannabinoid receptor THC receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	473
Amino acid sequence	MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
UniProt	P47746
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3037
IUPHAR	56
DrugBank	N/A

Ligand

Name	(2E,4E)-N-isobutyltetradeca-2,4-dienamide
Molecular formula	C18H33NO
IUPAC name	(2E,4E)-N-(2-methylpropyl)tetradeca-2,4-dienamide
Molecular weight	279.468
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	6.6
Synonyms	(E,E)-N-(2-Methylpropyl)-2,4-tetradecadienamide N-isobutyl-(2E,4E)-2,4-tetradecadienamide 2,4-Tetradecadienamide, N-isobutyl-, (E,E)- SCHEMBL15949868 (2E,4E)-N-Isobutyl-2,4-tetradecadienamide CHEMBL2442640 2,4-Tetradecadienamide, N-(2-methylpropyl)-, (2E,4E)- N-Isobutyl-(2E,4E)-tetradeca-2,4-dienamide AGJAUFUNZWHLKE-SQIWNDBBSA-N N-(2-Methylpropyl)-2,4-tetradecadienamide 2,4-Tetradecadienamide, N-(2-methylpropyl)-, (E,E)- N-Isobutyl-(2E,4E)-tetradecadienamide [ Show all ]
Inchi Key	AGJAUFUNZWHLKE-SQIWNDBBSA-N
Inchi ID	InChI=1S/C18H33NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-18(20)19-16-17(2)3/h12-15,17H,4-11,16H2,1-3H3,(H,19,20)/b13-12+,15-14+
PubChem CID	10731388
ChEMBL	CHEMBL2442640
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1400.0 nM	PMID24095014	ChEMBL

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