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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Parathyroid hormone/parathyroid hormone-related peptide receptor
Species	Homo sapiens (Human)
Gene	PTH1R
Synonym	PTH1 receptor PTHR PTH/PTHrP type I receptor PTH/PTHr receptor PPR Parathyroid hormone 1 receptor PTHR1 [ Show all ]
Disease	N/A
Length	593
Amino acid sequence	MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
UniProt	Q03431
Protein Data Bank	6fj3, 3h3g, 3c4m
GPCR-HGmod model	N/A
3D structure model	This structure is from PDB ID 6fj3.
BioLiP	BL0161387, BL0433539,BL0433540, BL0161388, BL0143680,BL0143682, BL0143681,BL0143683
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1793
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	MLS001179913
Molecular formula	C20H16N2O3
IUPAC name	2-(4-benzoylphenoxy)-N-pyridin-3-ylacetamide
Molecular weight	332.359
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.1
Synonyms	791127-70-3 HMS2904N24 Z31790281 AKOS034170900 MolPort-004-068-658 2-(4-benzoylphenoxy)-N-(3-pyridinyl)acetamide 2-(4-benzoylphenoxy)-N-pyridin-3-ylacetamide CHEMBL1424583 SR-01000806163-2 MCULE-8571444495 ZINC12476500 BDBM97142 SMR000595433 2-(4-benzoylphenoxy)-N-(3-pyridyl)acetamide 2-[4-(phenylcarbonyl)phenoxy]-N-pyridin-3-yl-ethanamide cid_2534340 SR-01000806163-3 AC1M8BLS SR-01000806163 2-(4-benzoylphenoxy)-N-(pyridin-3-yl)acetamide [ Show all ]
Inchi Key	FNMUQXAXWHYNQS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H16N2O3/c23-19(22-17-7-4-12-21-13-17)14-25-18-10-8-16(9-11-18)20(24)15-5-2-1-3-6-15/h1-13H,14H2,(H,22,23)
PubChem CID	2534340
ChEMBL	CHEMBL1424583
IUPHAR	N/A
BindingDB	97142
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Potency	19952.6 nM	PubChem BioAssay data set	ChEMBL

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