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Name | Probable G-protein coupled receptor 174 |
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Species | Homo sapiens (Human) |
Gene | GPR174 |
Synonym | FKSG79 GPR174 |
Disease | N/A |
Length | 333 |
Amino acid sequence | MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC |
UniProt | Q9BXC1 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9BXC1 |
3D structure model | This predicted structure model is from GPCR-EXP Q9BXC1. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562167 |
IUPHAR | 145 |
DrugBank | N/A |
Name | CHEMBL3577142 |
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Molecular formula | C24H45FNO8P |
IUPAC name | (2S)-2-amino-3-[[(2S)-2-fluoro-3-[(Z)-octadec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxypropanoic acid |
Molecular weight | 525.595 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 3 |
XlogP | 3.2 |
Synonyms | BDBM50096587 |
Inchi Key | DXUUBZLPNHDDHL-QXLPFXRRSA-N |
Inchi ID | InChI=1S/C24H45FNO8P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(25)19-33-35(30,31)34-20-22(26)24(28)29/h9-10,21-22H,2-8,11-20,26H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22-/m0/s1 |
PubChem CID | 122177494 |
ChEMBL | CHEMBL3577142 |
IUPHAR | N/A |
BindingDB | 50096587 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | <1000.0 nM | PMID25970039 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417