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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 1
Species	Mus musculus (Mouse)
Gene	Cnr1
Synonym	SKR6R Neuronal cannabinoid receptor Central cannabinoid receptor CB1R CB1 receptor CB1 CB-R Cann7 Cann6 Brain-type cannabinoid receptor THC receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	473
Amino acid sequence	MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
UniProt	P47746
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3037
IUPHAR	56
DrugBank	N/A

Ligand

Name	CHEMBL3633034
Molecular formula	C24H15Cl3F3N3O
IUPAC name	5-(4-chlorophenyl)-1-(3,5-dichlorophenyl)-4-methyl-N-[3-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Molecular weight	524.749
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	7.9
Synonyms	BDBM50130306
Inchi Key	DLXWZBNWPDMXTA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H15Cl3F3N3O/c1-13-21(23(34)31-19-4-2-3-15(9-19)24(28,29)30)32-33(20-11-17(26)10-18(27)12-20)22(13)14-5-7-16(25)8-6-14/h2-12H,1H3,(H,31,34)
PubChem CID	122194926
ChEMBL	CHEMBL3633034
IUPHAR	N/A
BindingDB	50130306
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	26.5 nM	PMID26200936	ChEMBL
Ki	27.0 nM	PMID26200936	BindingDB

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