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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Parathyroid hormone/parathyroid hormone-related peptide receptor
Species	Homo sapiens (Human)
Gene	PTH1R
Synonym	PTH1 receptor PTHR PTH/PTHrP type I receptor PTH/PTHr receptor PPR Parathyroid hormone 1 receptor PTHR1 [ Show all ]
Disease	N/A
Length	593
Amino acid sequence	MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
UniProt	Q03431
Protein Data Bank	6fj3, 3h3g, 3c4m
GPCR-HGmod model	N/A
3D structure model	This structure is from PDB ID 6fj3.
BioLiP	BL0161387, BL0433539,BL0433540, BL0161388, BL0143680,BL0143682, BL0143681,BL0143683
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1793
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	MLS000417396
Molecular formula	C27H21FN4O3S
IUPAC name	N-[2-(1H-benzimidazol-2-yl)phenyl]-2-[(4-fluoro-2-methylphenyl)sulfonylamino]benzamide
Molecular weight	500.548
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	5.5
Synonyms	HMS2513A04 N-[2-(1H-benzimidazol-2-yl)phenyl]-2-[(4-fluoro-2-methylphenyl)sulfonylamino]benzamide AKOS008027329 ZINC6016918 CHEMBL1563110 N-[2-(1H-benzimidazol-2-yl)phenyl]-2-[(4-fluoranyl-2-methyl-phenyl)sulfonylamino]benzamide HMS3375M15 Oprea1_088289 BDBM79555 MLS003910563 cid_2361995 N-[2-(1H-benzimidazol-2-yl)phenyl]-2-[(4-fluoro-2-methyl-phenyl)sulfonylamino]benzamide AC1M5WG0 MCULE-6057830799 SMR000242578 MolPort-005-899-939 [ Show all ]
Inchi Key	CZXNCDNJBVBOJX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H21FN4O3S/c1-17-16-18(28)14-15-25(17)36(34,35)32-22-11-5-3-9-20(22)27(33)31-21-10-4-2-8-19(21)26-29-23-12-6-7-13-24(23)30-26/h2-16,32H,1H3,(H,29,30)(H,31,33)
PubChem CID	2361995
ChEMBL	CHEMBL1563110
IUPHAR	N/A
BindingDB	79555
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Potency	50118.7 nM	PubChem BioAssay data set	ChEMBL

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