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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 1
Species	Mus musculus (Mouse)
Gene	Ccr1
Synonym	MIP1aR MIP-1alphaR MIP-1alpha/RANTES MIP-1alpha-R macrophage inflammatory protein-1 alpha receptor Macrophage inflammatory protein 1-alpha receptor CMKBR1 CKR1 CD191 CCR1 CCR-1 CC-CKR-1 CC CKR1 C-C CKR-1 RANTES-R [ Show all ]
Disease	N/A for non-human GPCRs
Length	355
Amino acid sequence	MEISDFTEAYPTTTEFDYGDSTPCQKTAVRAFGAGLLPPLYSLVFIIGVVGNVLVILVLMQHRRLQSMTSIYLFNLAVSDLVFLFTLPFWIDYKLKDDWIFGDAMCKLLSGFYYLGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGIITSIITWALAILASMPALYFFKAQWEFTHRTCSPHFPYKSLKQWKRFQALKLNLLGLILPLLVMIICYAGIIRILLRRPSEKKVKAVRLIFAITLLFFLLWTPYNLSVFVSAFQDVLFTNQCEQSKQLDLAMQVTEVIAYTHCCVNPIIYVFVGERFWKYLRQLFQRHVAIPLAKWLPFLSVDQLERTSSISPSTGEHELSAGF
UniProt	P51675
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3872
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL33929
Molecular formula	C29H37Cl2N2O2+
IUPAC name	2,7-dichloro-N-[1-(cyclooctylmethyl)-1-methylpiperidin-1-ium-4-yl]-9H-xanthene-9-carboxamide
Molecular weight	516.527
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	7.8
Synonyms	BDBM50098630 1-Cyclooctylmethyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-methyl-piperidinium; iodide CHEMBL1178597
Inchi Key	GAWADCCAEQQLNX-UHFFFAOYSA-O
Inchi ID	InChI=1S/C29H36Cl2N2O2/c1-33(19-20-7-5-3-2-4-6-8-20)15-13-23(14-16-33)32-29(34)28-24-17-21(30)9-11-26(24)35-27-12-10-22(31)18-25(27)28/h9-12,17-18,20,23,28H,2-8,13-16,19H2,1H3/p+1
PubChem CID	10580015
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50098630
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	710.0 nM	PMID11311066	BindingDB

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