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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Oxoeicosanoid receptor 1
Species	Homo sapiens (Human)
Gene	OXER1
Synonym	R527 oxoeicosanoid (OXE) receptor 1 OXE receptor hGPCR48 GPR170 G-protein coupled receptor TG1019 G-protein coupled receptor R527 G-protein coupled receptor 170 5-oxo-ETE receptor 5-oxo-ETE G-protein coupled receptor TG1019 [ Show all ]
Disease	N/A
Length	423
Amino acid sequence	MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
UniProt	Q8TDS5
Protein Data Bank	N/A
GPCR-HGmod model	Q8TDS5
3D structure model	This predicted structure model is from GPCR-EXP Q8TDS5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1628461
IUPHAR	271
DrugBank	N/A

Ligand

Name	CHEMBL3115773
Molecular formula	C20H25NO3
IUPAC name	5-(2-hexylquinolin-3-yl)-5-oxopentanoic acid
Molecular weight	327.424
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.5
Synonyms	CNBJHCZSESRTBT-UHFFFAOYSA-N 5-(2-Hexyl-quinolin-3-yl)-5-oxo-pentanoic acid SCHEMBL287359 BDBM50446978
Inchi Key	CNBJHCZSESRTBT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H25NO3/c1-2-3-4-5-11-18-16(19(22)12-8-13-20(23)24)14-15-9-6-7-10-17(15)21-18/h6-7,9-10,14H,2-5,8,11-13H2,1H3,(H,23,24)
PubChem CID	49802030
ChEMBL	CHEMBL3115773
IUPHAR	N/A
BindingDB	50446978
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<30000.0 nM	PMID24351031	BindingDB,ChEMBL

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