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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A3
Species	Homo sapiens (Human)
Gene	ADORA3
Synonym	ARA3 Adenosine receptor A3 A3AR A3 receptor TGPCR1
Disease	Cerebrovascular ischaemia Malaria Ischemia Inflammation Hepatocellular carcinoma; Hepatitis C virus infection Glaucoma Cancer [ Show all ]
Length	318
Amino acid sequence	MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
UniProt	P0DMS8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	T36059
ChEMBL	CHEMBL256
IUPHAR	21
DrugBank	BE0000354

Ligand

Name	4-Damp methiodide
Molecular formula	C21H26INO2
IUPAC name	(1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate;iodide
Molecular weight	451.348
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	None
Synonyms	CHEBI:73340 HMS3266E10 N,N-dimethyl-4-(diphenylacetoxy)piperidinium iodide SR-01000075326-1 1,1-dimethyl-4-diphenylacetoxypiperidinium iodide 4-DAMP methyliodide AC1MHZ3P BN0026 D-104 LP00407 Piperidinium, 4-((diphenylacetyl)oxy)-1,1-dimethyl-, iodide 4-((Diphenylacetyl)oxy)-1,1-dimethylpiperidinium iodide 4-DIPHENYLACETOXY-N-METHYL-PIPERIDINE METHIODIDE CCG-221711 HMS2234J07 MLS000859984 SMR000326843 4-DAMP iodide 4-[(Diphenylacetyl)oxy]-1,1-dimethyl-piperidinium iodide HMS3369K06 NCGC00093833-01 SR-01000075326-3 1,1-dimethyl-4-diphenylacetoxypiperidiniumiodide 4-DAMP, >=98% (HPLC) AKOS024458363 C-56134 EU-0100407 LS-173781 REGID_for_CID_3014059 4-(2,2-diphenylacetoxy)-1,1-dimethylpiperidinium iodide 4-Diphenylacetoxy-N-methylpiperidine methiodide CCG-222526 HMS3261A16 MolPort-003-940-940 SR-01000075326 (1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate iodide 81405-11-0 (Parent) CHEMBL76897 J-012645 NCGC00261092-01 Tox21_500407 1952-15-4 4-diphenylacetoxy-1,1-dimethylpiperidinium iodide B6317 C21H26NO2.I FT-0742369 MFCD00078564 SCHEMBL3987354 4-DAMP 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethylpiperidin-1-ium iodide [ Show all ]
Inchi Key	WWJHRSCUAQPFQO-UHFFFAOYSA-M
Inchi ID	InChI=1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1
PubChem CID	3014059
ChEMBL	CHEMBL76897
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1.9 nM	PMID16250647	ChEMBL

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