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Name | Somatostatin receptor type 5 |
---|---|
Species | Homo sapiens (Human) |
Gene | SSTR5 |
Synonym | SOMATO SS-5-R SS5-R SS5R SST5 receptor |
Disease | N/A |
Length | 364 |
Amino acid sequence | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL |
UniProt | P35346 |
Protein Data Bank | N/A |
GPCR-HGmod model | P35346 |
3D structure model | This predicted structure model is from GPCR-EXP P35346. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1792 |
IUPHAR | 359 |
DrugBank | BE0002147 |
Name | CHEMBL3323082 |
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Molecular formula | C30H24FN7O2 |
IUPAC name | 2-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyridine-4-carboxylic acid |
Molecular weight | 533.567 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 4 |
XlogP | 0.7 |
Synonyms | BDBM50053690 |
Inchi Key | UHWQSESKOKODEV-HLADLETHSA-N |
Inchi ID | InChI=1S/C30H24FN7O2/c1-38-16-19(14-34-38)30(26-12-18(29(39)40)10-11-32-26)27-22(21-4-2-3-5-23(21)35-27)13-24(37-30)28-33-15-25(36-28)17-6-8-20(31)9-7-17/h2-12,14-16,24,35,37H,13H2,1H3,(H,33,36)(H,39,40)/t24-,30+/m1/s1 |
PubChem CID | 86279005 |
ChEMBL | CHEMBL3323082 |
IUPHAR | N/A |
BindingDB | 50053690 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | <10000.0 nM | PMID25050159 | BindingDB,ChEMBL |
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