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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Probable C-C chemokine receptor type 3
Species	Mus musculus (Mouse)
Gene	Ccr3
Synonym	CC-CKR-3 MIP-1alphaRL-2 (mouse) MIP-1 alpha RL2 Macrophage inflammatory protein 1-alpha receptor-like 2 CKR3 chemokine (C-C motif) receptor 3 CC CKR3 CD193 CCR3 CCR-3 C-C CKR-3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF
UniProt	P51678
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3406
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3355942
Molecular formula	C24H29FN2S
IUPAC name	2-ethyl-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-1H-indole
Molecular weight	396.568
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50041203 SCHEMBL1097888
Inchi Key	NMYOEGLWLBKTCW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29FN2S/c1-2-22-24(21-6-3-4-7-23(21)26-22)18-12-15-27(16-13-18)14-5-17-28-20-10-8-19(25)9-11-20/h3-4,6-11,18,26H,2,5,12-17H2,1H3
PubChem CID	66906657
ChEMBL	CHEMBL3355942
IUPHAR	N/A
BindingDB	50041203
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	400.0 nM	PMID25497216	BindingDB,ChEMBL

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