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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Probable C-C chemokine receptor type 3
Species	Mus musculus (Mouse)
Gene	Ccr3
Synonym	CC-CKR-3 MIP-1alphaRL-2 (mouse) MIP-1 alpha RL2 Macrophage inflammatory protein 1-alpha receptor-like 2 CKR3 chemokine (C-C motif) receptor 3 CC CKR3 CD193 CCR3 CCR-3 C-C CKR-3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF
UniProt	P51678
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3406
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3355937
Molecular formula	C25H30FN3OS
IUPAC name	4-[3-[4-(2-ethyl-6-fluoro-1H-indol-3-yl)piperidin-1-yl]propylsulfanyl]benzamide
Molecular weight	439.593
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.0
Synonyms	BDBM50041167
Inchi Key	CRBGNOGVLJKUSQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30FN3OS/c1-2-22-24(21-9-6-19(26)16-23(21)28-22)17-10-13-29(14-11-17)12-3-15-31-20-7-4-18(5-8-20)25(27)30/h4-9,16-17,28H,2-3,10-15H2,1H3,(H2,27,30)
PubChem CID	118721188
ChEMBL	CHEMBL3355937
IUPHAR	N/A
BindingDB	50041167
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1300.0 nM	PMID25497216	BindingDB,ChEMBL

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