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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SR-02000000357
Molecular formula	C19H16Cl2N2O2
IUPAC name	5-chloro-4-(4-chlorophenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-one
Molecular weight	375.249
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.4
Synonyms	5-chloro-4-(4-chlorophenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-one SR-02000000357-1 BDBM75889 5-chloranyl-4-(4-chloranylphenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-one cid_46172932 5-chloro-4-(4-chlorophenoxy)-2-p-cumenyl-pyridazin-3-one SR-02000000357-2 5-chloro-4-(4-chlorophenoxy)-2-(4-propan-2-ylphenyl)-3-pyridazinone CHEMBL1729749 [ Show all ]
Inchi Key	CJWGCKWFQNORJC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16Cl2N2O2/c1-12(2)13-3-7-15(8-4-13)23-19(24)18(17(21)11-22-23)25-16-9-5-14(20)6-10-16/h3-12H,1-2H3
PubChem CID	46172932
ChEMBL	CHEMBL1729749
IUPHAR	N/A
BindingDB	75889
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1400.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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