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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701960
Molecular formula	C15H15Br2N3O
IUPAC name	3,5-dibromo-N-[4-[(2S)-morpholin-2-yl]phenyl]pyridin-2-amine
Molecular weight	413.113
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.1
Synonyms	US8802673, 61 BDBM129419 SCHEMBL12609828
Inchi Key	CJPKOIJMBFKKCS-CQSZACIVSA-N
Inchi ID	InChI=1S/C15H15Br2N3O/c16-11-7-13(17)15(19-8-11)20-12-3-1-10(2-4-12)14-9-18-5-6-21-14/h1-4,7-8,14,18H,5-6,9H2,(H,19,20)/t14-/m1/s1
PubChem CID	68325589
ChEMBL	CHEMBL3701960
IUPHAR	N/A
BindingDB	129419
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	502.4 nM	, None	BindingDB,ChEMBL

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