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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SR-02000000480
Molecular formula	C20H17ClN2O5
IUPAC name	ethyl 3-[4-chloro-5-(4-methoxyphenoxy)-6-oxopyridazin-1-yl]benzoate
Molecular weight	400.815
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.8
Synonyms	ethyl 3-[4-chloranyl-5-(4-methoxyphenoxy)-6-oxidanylidene-pyridazin-1-yl]benzoate SR-02000000480-1 CHEMBL1698073 ethyl 3-[4-chloro-5-(4-methoxyphenoxy)-6-oxopyridazin-1-yl]benzoate 3-[4-chloro-5-(4-methoxyphenoxy)-6-oxo-1-pyridazinyl]benzoic acid ethyl ester BDBM75944 cid_46850890 3-[4-chloro-6-keto-5-(4-methoxyphenoxy)pyridazin-1-yl]benzoic acid ethyl ester [ Show all ]
Inchi Key	CIILEJHKOUMREY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H17ClN2O5/c1-3-27-20(25)13-5-4-6-14(11-13)23-19(24)18(17(21)12-22-23)28-16-9-7-15(26-2)8-10-16/h4-12H,3H2,1-2H3
PubChem CID	46850890
ChEMBL	CHEMBL1698073
IUPHAR	N/A
BindingDB	75944
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1100.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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