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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL320900
Molecular formula	C33H28ClN5O3S
IUPAC name	ethyl 4-(2-chlorophenyl)-6-methyl-2-[4-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate
Molecular weight	610.129
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	7.1
Synonyms	BDBM50004641 4-(2-Chloro-phenyl)-6-methyl-2-[4-(6-methyl-imidazo[2,1-b]thiazol-5-yl)-phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester
Inchi Key	CFSAOLMFARGDEU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H28ClN5O3S/c1-4-42-32(41)28-27(23-9-5-6-10-24(23)34)26(31(40)38-25-11-7-8-16-35-25)19(2)36-29(28)21-12-14-22(15-13-21)30-20(3)37-33-39(30)17-18-43-33/h5-18,27,36H,4H2,1-3H3,(H,35,38,40)
PubChem CID	15005345
ChEMBL	CHEMBL320900
IUPHAR	N/A
BindingDB	50004641
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	5.0 nM	PMID1507200	BindingDB,ChEMBL

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