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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Nociceptin receptor
Species	Cavia porcellus (Guinea pig)
Gene	OPRL1
Synonym	Kappa-type 3 opioid receptor KOR-3 Orphanin FQ receptor XOR
Disease	N/A for non-human GPCRs
Length	370
Amino acid sequence	MESLFPAPFWEVLYGSHLQGNLSLLSPNHSGLPPHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQATDILLGFWPFGNTLCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALALVVGVPVAIMGSAQVEDEEIECLVEIPDPQDYWGPVFAVSIFLFSFIIPVLIISVCYSLMIRRLHGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETTVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVALGCKTTETVPRPA
UniProt	P47748
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5492
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	DM3B6S
Molecular formula	C24H25NO7S
IUPAC name	[(4R,4aR,7S,7aR,12bS)-3-methyl-7-sulfooxy-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-9-yl] benzoate
Molecular weight	471.524
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	0.9
Synonyms	D0IC5F CHEMBL213737 SCHEMBL7669030
Inchi Key	YEYZQNSVGVDYOU-MJFIPZRTSA-N
Inchi ID	InChI=1S/C24H25NO7S/c1-25-12-11-24-16-8-10-19(32-33(27,28)29)22(24)31-21-18(9-7-15(20(21)24)13-17(16)25)30-23(26)14-5-3-2-4-6-14/h2-7,9,16-17,19,22H,8,10-13H2,1H3,(H,27,28,29)/t16-,17+,19-,22-,24-/m0/s1
PubChem CID	21345767
ChEMBL	CHEMBL213737
IUPHAR	N/A
BindingDB	50189253
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	822.0 nM	PMID16777416	BindingDB,ChEMBL

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