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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1441254
Molecular formula	C17H13ClN2O3
IUPAC name	5-chloro-4-(4-methoxyphenoxy)-2-phenylpyridazin-3-one
Molecular weight	328.752
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.6
Synonyms	KS-000039SH SR-01000692203-3 AKOS005095267 MolPort-002-872-090 SMR000179332 5-chloro-4-(4-methoxyphenoxy)-2-phenyl-3(2H)-pyridazinone MCULE-9419118685 ZINC1023864 5M-594S BDBM50401588 Oprea1_367843 42190-48-7 HMS2310B11 SR-01000692203 5-chloro-4-(4-methoxyphenoxy)-2-phenylpyridazin-3-one MLS000326761 AC1MCSS9 REGID_for_CID_2800329 5-chloro-4-(4-methoxyphenoxy)-2-phenyl-2,3-dihydropyridazin-3-one [ Show all ]
Inchi Key	CDMJYZVKNAEVQP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H13ClN2O3/c1-22-13-7-9-14(10-8-13)23-16-15(18)11-19-20(17(16)21)12-5-3-2-4-6-12/h2-11H,1H3
PubChem CID	2800329
ChEMBL	CHEMBL1441254
IUPHAR	N/A
BindingDB	50401588
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	13000.0 nM	PMID23079522	BindingDB,ChEMBL

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