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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 5A
Species	Rattus norvegicus (Rat)
Gene	Htr5a
Synonym	5-HT5A receptor REC17 MR22 Htr5 5-HT-5A 5HT5- 5-HT5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 5-HT5alpha serotonin receptor 5A [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLLVLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFGWGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVSPIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
UniProt	P35364
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4655
IUPHAR	10
DrugBank	N/A

Ligand

Name	CHEMBL334553
Molecular formula	C16H25NO
IUPAC name	(1R,2R)-2-(3-methoxyphenyl)-N,N-dipropylcyclopropan-1-amine
Molecular weight	247.382
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM50288774 [(1R,2R)-2-(3-Methoxy-phenyl)-cyclopropyl]-dipropyl-amine
Inchi Key	CDBKSCIFVPNNTJ-HZPDHXFCSA-N
Inchi ID	InChI=1S/C16H25NO/c1-4-9-17(10-5-2)16-12-15(16)13-7-6-8-14(11-13)18-3/h6-8,11,15-16H,4-5,9-10,12H2,1-3H3/t15-,16-/m1/s1
PubChem CID	44355201
ChEMBL	CHEMBL334553
IUPHAR	N/A
BindingDB	50288774
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	736.0 nM	, Bioorg. Med. Chem. Lett., (1996) 6:4:415	BindingDB,ChEMBL

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