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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP1 subtype
Species	Mus musculus (Mouse)
Gene	Ptger1
Synonym	EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa Prostanoid EP1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	405
Amino acid sequence	MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLAQVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGRYELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL
UniProt	P35375
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2181
IUPHAR	340
DrugBank	N/A

Ligand

Name	CHEMBL186925
Molecular formula	C27H25NO4
IUPAC name	2-[2-methyl-1-[4-(3-phenylpropoxy)benzoyl]indol-4-yl]acetic acid
Molecular weight	427.5
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.7
Synonyms	{2-Methyl-1-[4-(3-phenyl-propoxy)-benzoyl]-1H-indol-4-yl}-acetic acid BDBM50152519 SCHEMBL5852450
Inchi Key	WZVODYACIPKUAB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H25NO4/c1-19-17-24-22(18-26(29)30)10-5-11-25(24)28(19)27(31)21-12-14-23(15-13-21)32-16-6-9-20-7-3-2-4-8-20/h2-5,7-8,10-15,17H,6,9,16,18H2,1H3,(H,29,30)
PubChem CID	21974464
ChEMBL	CHEMBL186925
IUPHAR	N/A
BindingDB	50152519
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	7700.0 nM	PMID15341946	BindingDB,ChEMBL

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