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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melatonin receptor type 1B
Species	Gallus gallus (Chicken)
Gene
Synonym	Mel-1B-R Mel1b receptor
Disease	N/A for non-human GPCRs
Length	289
Amino acid sequence	GNAFVVSLALADLVVALYPYPLVLLAIFHNGWTLGEMHCKVSGFVMGLSVIGSIFNITAIAINRYCYICHSFAYDKVYSCWNTMLYVSLIWVLTVIATVPNFFVGSLKYDPRIYSCTFVQTASSYYTIAVVVIHFIVPITVVSFCYLRIWVLVLQVRRRVKSETKPRLKPSDFRNFLTMFVVFVIFAFCWAPLNFIGLAVAINPSEMAPKVPEWLFIISYFMAYFNSCLNAIIYGLLNQNFRNEYKRILMSLWMPRLFFQDTSKGGTDGQKSKPSPALNNNDQMKTDTL
UniProt	P51050
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4466
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	luzindole
Molecular formula	C19H20N2O
IUPAC name	N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
Molecular weight	292.382
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	3.6
Synonyms	KS-00001828 N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide NCGC00024838-02 ST50405851 2-Benzyl-N-acetyltryptamine AN-25006 N-Acetyl-2-benzyltryptamine PDSP2_001771 ZB000552 AC1L3U3V BN0311 DTXSID40151969 HMS3266N04 MolPort-003-848-430 N-{2-[2-benzylindol-3-yl]ethyl}acetamide SR-01000597433 117946-91-5 AM20020263 CHEBI:131788 L000360 N-0774 NSC_122162 Tocris-0877 7354AH B6483 CHEMBL286615 Luzindole, >=90% N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide RT-013606 ZINC3941 Acetamide, N-(2-(2-(phenylmethyl)-1H-indol-3-yl)ethyl)- BRD-K67013324-001-01-5 FT-0628053 J-003685 N 0774 NCGC00024838-01 SR-01000597433-1 AMOT0032 CHEBI:93173 L0316 N-Acetyl-2-benzyl-tryptamine PDSP1_001788 TRA0042414 BDBM85065 CTK8E7069 MFCD00672498 N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide SCHEMBL4869000 AKOS024458674 CAS_117946-91-5 GTPL1363 [ Show all ]
Inchi Key	WVVXBPKOIZGVNS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
PubChem CID	122162
ChEMBL	CHEMBL286615
IUPHAR	1363
BindingDB	85065
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1737.8 nM	PMID9840420	BindingDB

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