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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 11
Species	Homo sapiens (Human)
Gene	P2RY11
Synonym	P2Y11 P2Y11 receptor purinergic receptor P2Y, G-protein coupled, 11
Disease	N/A
Length	374
Amino acid sequence	MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ
UniProt	Q96G91
Protein Data Bank	N/A
GPCR-HGmod model	Q96G91
3D structure model	This predicted structure model is from GPCR-EXP Q96G91.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4867
IUPHAR	327
DrugBank	BE0005499

Ligand

Name	CHEMBL2111533
Molecular formula	C12H18N5O12P3
IUPAC name	[[(1R,2R,3S,4R,5S)-4-(6-aminopurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular weight	517.22
Hydrogen bond acceptor	16
Hydrogen bond donor	7
XlogP	-5.3
Synonyms	BDBM50409486 SCHEMBL19503936
Inchi Key	WOSUREDDZAHDRQ-PHPBVZTRSA-N
Inchi ID	InChI=1S/C12H18N5O12P3/c13-10-6-11(15-3-14-10)17(4-16-6)7-5-1-12(5,9(19)8(7)18)2-27-31(23,24)29-32(25,26)28-30(20,21)22/h3-5,7-9,18-19H,1-2H2,(H,23,24)(H,25,26)(H2,13,14,15)(H2,20,21,22)/t5-,7-,8+,9+,12+/m1/s1
PubChem CID	10994891
ChEMBL	CHEMBL2111533
IUPHAR	N/A
BindingDB	50409486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Activity	34.5 %	PMID11754592	ChEMBL
EC50	17250.0 nM	PMID11754592	BindingDB,ChEMBL

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