You can:
Name | 5-hydroxytryptamine receptor 2A |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Htr2a |
Synonym | serotonin 5HT-2 receptor 5Ht-2 'D' receptor 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 5-HT2A receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 471 |
Amino acid sequence | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV |
UniProt | P14842 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL322 |
IUPHAR | 6 |
DrugBank | N/A |
Name | 5-Carboxamidotryptamine |
---|---|
Molecular formula | C11H13N3O |
IUPAC name | 3-(2-aminoethyl)-1H-indole-5-carboxamide |
Molecular weight | 203.245 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 3 |
XlogP | -0.6 |
Synonyms | WKZLNEWVIAGNAW-UHFFFAOYSA-N 1H-Indole-5-carboxamide, 3-(2-aminoethyl)- 5-Carboxamide tryptamine AC1Q5DOI Lopac0_000352 [ Show all ] |
Inchi Key | WKZLNEWVIAGNAW-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) |
PubChem CID | 1809 |
ChEMBL | CHEMBL18840 |
IUPHAR | 4 |
BindingDB | 21392 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 21877.6 nM | Bioorg. Med. Chem. Lett., (1994) 4:10:1207 | ChEMBL |
IC50 | 21878.0 nM | N/A | BindingDB |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417