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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 2
Species	Homo sapiens (Human)
Gene	LPAR2
Synonym	endothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4 LPA receptor 2 LPA-2 Edg4 Lysophosphatidic acid receptor Edg-4 Pbx4 pre-B-cell leukemia transcription factor 4 LPA2 receptor [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
UniProt	Q9HBW0
Protein Data Bank	N/A
GPCR-HGmod model	Q9HBW0
3D structure model	This predicted structure model is from GPCR-EXP Q9HBW0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3724
IUPHAR	273
DrugBank	N/A

Ligand

Name	Tetradecylphosphonic acid
Molecular formula	C14H31O3P
IUPAC name	tetradecylphosphonic acid
Molecular weight	278.373
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.1
Synonyms	STL557036 WLN: QPQO&14 ACM4671754 FT-0693992 NSC127409 Phosphonic acid, tetradecyl- Tetradecyl-phosphonic acid 1956AH BDBM50170846 D0P7GR LS-106793 SR-01000946789 Tetradecylphosphonic acid, 97% C-52694 EINECS 225-118-1 n-Tetradecylphosphonic acid Tetradecanephosphonic acid ZINC36178975 1-Tetradecanephosphonic acid AKOS015918250 CHEMBL190999 HMS3650I03 P-tetradecyl-Phosphonic acid RT-004112 tetradecylphosphonate 4-04-00-03566 (Beilstein Handbook Reference) BRN 1784271 DB-070750 MFCD00015834 SR-01000946789-1 Tetradecylphosphonic acid, 99+ % AC1L2V5G C14H31O3P F0001-1259 NSC-127409 Phosphonic acid, P-tetradecyl- Tetradecyl phosphonic acid 1-Tetradecylphosphonic Acid BBL103226 CTK3J7960 I14-8487 SCHEMBL19906 4671-75-4 BVQJQTMSTANITJ-UHFFFAOYSA-N DTXSID7063550 MolPort-006-116-374 [ Show all ]
Inchi Key	BVQJQTMSTANITJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H31O3P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18(15,16)17/h2-14H2,1H3,(H2,15,16,17)
PubChem CID	78401
ChEMBL	CHEMBL190999
IUPHAR	N/A
BindingDB	50170846
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	5500.0 nM	PMID16033271	BindingDB,ChEMBL
Ki	3550.0 nM	PMID16033271	BindingDB,ChEMBL

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