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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Oryctolagus cuniculus (Rabbit)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
UniProt	P34976
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3948
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL169221
Molecular formula	C32H37N5O6S
IUPAC name	butyl N-[2-[4-[[6-(ethylcarbamoylamino)-4-oxo-2-propylquinazolin-3-yl]methyl]phenyl]phenyl]sulfonylcarbamate
Molecular weight	619.737
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.6
Synonyms	BDBM50282472 L007602
Inchi Key	BRAZUXALZLWNTL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H37N5O6S/c1-4-7-19-43-32(40)36-44(41,42)28-12-9-8-11-25(28)23-15-13-22(14-16-23)21-37-29(10-5-2)35-27-18-17-24(20-26(27)30(37)38)34-31(39)33-6-3/h8-9,11-18,20H,4-7,10,19,21H2,1-3H3,(H,36,40)(H2,33,34,39)
PubChem CID	44210586
ChEMBL	CHEMBL169221
IUPHAR	N/A
BindingDB	50282472
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	0.18 nM	Bioorg. Med. Chem. Lett., (1994) 4:1:81	ChEMBL
IC50	0.18 nM	N/A	BindingDB

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