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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701950
Molecular formula	C20H20ClN3O
IUPAC name	N-[(2-chloroquinolin-3-yl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	353.85
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.7
Synonyms	SCHEMBL12609839 US8802673, 51 BDBM129409
Inchi Key	BQDOGNWVKQRWBL-LJQANCHMSA-N
Inchi ID	InChI=1S/C20H20ClN3O/c21-20-16(11-15-3-1-2-4-18(15)24-20)12-23-17-7-5-14(6-8-17)19-13-22-9-10-25-19/h1-8,11,19,22-23H,9-10,12-13H2/t19-/m1/s1
PubChem CID	86766836
ChEMBL	CHEMBL3701950
IUPHAR	N/A
BindingDB	129409
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	280.3 nM	, None	BindingDB,ChEMBL

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