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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melanin-concentrating hormone receptor 1
Species	Homo sapiens (Human)
Gene	MCHR1
Synonym	SLC-1 Somatostatin receptor-like protein MCHR-1 MCHR MCH1R MCH1 receptor MCH-R1 MCH-1R MCH receptor 1 GPR24 G-protein coupled receptor 24 G protein-coupled receptor 24 [ Show all ]
Disease	Obesity Obesity; Anxiety; Depression
Length	422
Amino acid sequence	MSVGAMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESKGT
UniProt	Q99705
Protein Data Bank	N/A
GPCR-HGmod model	Q99705
3D structure model	This predicted structure model is from GPCR-EXP Q99705.
BioLiP	N/A
Therapeutic Target Database	T09572
ChEMBL	CHEMBL344
IUPHAR	280
DrugBank	BE0003478

Ligand

Name	CHEMBL3219001
Molecular formula	C34H31ClN4O2
IUPAC name	N-[3-[1-[[4-[1-(4-chlorophenyl)benzimidazole-2-carbonyl]phenyl]methyl]piperidin-4-yl]phenyl]acetamide
Molecular weight	563.098
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.7
Synonyms	N/A
Inchi Key	ADQFOTNYOVDLON-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H31ClN4O2/c1-23(40)36-29-6-4-5-27(21-29)25-17-19-38(20-18-25)22-24-9-11-26(12-10-24)33(41)34-37-31-7-2-3-8-32(31)39(34)30-15-13-28(35)14-16-30/h2-16,21,25H,17-20,22H2,1H3,(H,36,40)
PubChem CID	90666098
ChEMBL	CHEMBL3219001
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	34.0 nM	MedChemComm, (2011) 2:5:385	ChEMBL
IC50	217.0 nM	MedChemComm, (2011) 2:5:385	ChEMBL

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