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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucose-dependent insulinotropic receptor
Species	Rattus norvegicus (Rat)
Gene	Gpr119
Synonym	G protein-coupled receptor 119 G-protein coupled receptor 119 G-protein coupled receptor 2 glucose-dependent insulinotropic receptor GPCR2 GPR119 [ Show all ]
Disease	N/A for non-human GPCRs
Length	468
Amino acid sequence	MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGGCIAGLWLISYLIGFLPLGVSIFQQTTYHGPCTFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQHIRKMEHAGAMVGACRPPRPVNDFKAVRTVSVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLCHMALGLLADGSTQPQIETLKGKEERKKVGRKTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDACDTQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDTQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTSSLVTGQTEQTPLKRANMSDPLRTCRG
UniProt	Q7TQN8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5262
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1773279
Molecular formula	C24H32N6O4S
IUPAC name	tert-butyl 4-[[methyl-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]methyl]piperidine-1-carboxylate
Molecular weight	500.618
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.2
Synonyms	142894-EP2292620A2 4-({[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-methyl-amino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester 142894-EP2287165A2 BDBM50343457 143630-EP2287166A2 SCHEMBL389100 4-({[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-methylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester 142894-EP2287166A2 143630-EP2292620A2 tert-butyl 4-((methyl(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)methyl)piperidine-1-carboxylate [ Show all ]
Inchi Key	QNAOVZXVOZZSTA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H32N6O4S/c1-24(2,3)34-23(31)29-12-10-17(11-13-29)15-28(4)21-20-14-27-30(22(20)26-16-25-21)18-6-8-19(9-7-18)35(5,32)33/h6-9,14,16-17H,10-13,15H2,1-5H3
PubChem CID	53630395
ChEMBL	CHEMBL1773279
IUPHAR	N/A
BindingDB	50343457
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ratio EC50	3.0 -	PMID21444206	ChEMBL

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