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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1998041
Molecular formula	C21H14BrFN2O
IUPAC name	5-bromo-4-(3-fluorophenyl)-2-(naphthalen-1-ylmethyl)pyridazin-3-one
Molecular weight	409.258
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.9
Synonyms	SR-02000001653 SR-02000001653-1
Inchi Key	BNFJKQUMVJNVGZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H14BrFN2O/c22-19-12-24-25(21(26)20(19)15-7-4-9-17(23)11-15)13-16-8-3-6-14-5-1-2-10-18(14)16/h1-12H,13H2
PubChem CID	53364419
ChEMBL	CHEMBL1998041
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	533.0 nM	PubChem BioAssay data set	ChEMBL

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