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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 7
Species	Cavia porcellus (Guinea pig)
Gene	HTR7
Synonym	5-HT-7 5-HT-X 5-HT7 Serotonin receptor 7
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MMGVNSSGRPDLYGHLHSILLPGRGLPDWSPDGGADPGVSTWTPRLLSGVPEVAASPSPSWDGTWDNVSGCGEQINYGRAEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVIPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMPKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIYKAARKSAAKHKFPGFPRVQPESIISLNGMVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTACSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPECVLQNSDYCRKKGHDS
UniProt	P50407
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5494
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	5-Carboxamidotryptamine maleate
Molecular formula	C15H17N3O5
IUPAC name	3-(2-aminoethyl)-1H-indole-5-carboxamide;(Z)-but-2-enedioic acid
Molecular weight	319.317
Hydrogen bond acceptor	6
Hydrogen bond donor	5
XlogP	None
Synonyms	1H-Indole-5-carboxamide, 3-(2-aminoethyl)-, (2Z)-2-butenedioate (1:1) CCG-221656 NCGC00261037-01 5-CT; AH-21467 EU-0100352 SR-01000075545-1 BN0033 MolPort-003-940-625 UNII-6PED53BA7M SCHEMBL11363734 6PED53BA7M HMS3261G05 SR-01000075545-3 C-117 NCGC00093788-01 5-Carboxamidotryptamine maleate salt, powder, >=98% (HPLC) CHEMBL1256863 SR-01000075545 AKOS024458233 LP00352 Tox21_500352 [ Show all ]
Inchi Key	PZQZSWAOVAMBQM-BTJKTKAUSA-N
Inchi ID	InChI=1S/C11H13N3O.C4H4O4/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10;5-3(6)1-2-4(7)8/h1-2,5-6,14H,3-4,12H2,(H2,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-
PubChem CID	11709509
ChEMBL	CHEMBL1256863
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Activity	40.0 %	PMID22738316	ChEMBL

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