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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Sus scrofa (Pig)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P50130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5067
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1258155
Molecular formula	C23H28ClNO
IUPAC name	4-[4-(4-chlorophenyl)piperidin-1-yl]-1-(2,5-dimethylphenyl)butan-1-one
Molecular weight	369.933
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	5.5
Synonyms	BDBM50328452 4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-(2,5-dimethylphenyl)-butan-1-one
Inchi Key	PZBBMWTZUNRBLR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28ClNO/c1-17-5-6-18(2)22(16-17)23(26)4-3-13-25-14-11-20(12-15-25)19-7-9-21(24)10-8-19/h5-10,16,20H,3-4,11-15H2,1-2H3
PubChem CID	52940985
ChEMBL	CHEMBL1258155
IUPHAR	N/A
BindingDB	50328452
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	690.0 nM	PMID20839776	BindingDB,ChEMBL

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