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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701919
Molecular formula	C18H22N2O2
IUPAC name	N-[(4-methoxyphenyl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	298.386
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.6
Synonyms	BDBM129378 SCHEMBL12610144 US8802673, 20
Inchi Key	BLNVIMYBVSDGSQ-GOSISDBHSA-N
Inchi ID	InChI=1S/C18H22N2O2/c1-21-17-8-2-14(3-9-17)12-20-16-6-4-15(5-7-16)18-13-19-10-11-22-18/h2-9,18-20H,10-13H2,1H3/t18-/m1/s1
PubChem CID	68325799
ChEMBL	CHEMBL3701919
IUPHAR	N/A
BindingDB	129378
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	764.1 nM	, None	BindingDB,ChEMBL

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