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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 1
Species	Rattus norvegicus (Rat)
Gene	Cnr1
Synonym	SKR6R Neuronal cannabinoid receptor Central cannabinoid receptor CB1R CB1 receptor CB1 CB-R Cann7 Cann6 Brain-type cannabinoid receptor THC receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	473
Amino acid sequence	MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
UniProt	P20272
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3571
IUPHAR	56
DrugBank	N/A

Ligand

Name	(2s)-2-amino-4-sulfinobutanoic acid
Molecular formula	C4H9NO4S
IUPAC name	(2S)-2-amino-4-sulfinobutanoic acid
Molecular weight	167.179
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.8
Synonyms	2686-70-6 CHEMBL1516176 NCGC00163274-02 AC1Q5QML FT-0639107 PDSP2_001256 Butanoic acid, 2-amino-4-sulfino-, (2S)- L-Homocysteinesulphinic Acid ZINC25720432 CTK4F8661 PDSP1_001272 AKOS030568392 L-homocysteine sulfinic acid PDSP2_001260 Butanoic acid,2-amino-4-sulfino-, (2S)- NCGC00163274-01 AC1L2PR4 FT-0634441 PDSP1_001276 BDBM86201 L-Homocysteinesulfinic acid SCHEMBL10135851 [ Show all ]
Inchi Key	PDNJLMZEGXHSCU-VKHMYHEASA-N
Inchi ID	InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1
PubChem CID	75896
ChEMBL	N/A
IUPHAR	N/A
BindingDB	86201
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID12649361	BindingDB

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