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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1B) dopamine receptor
Species	Homo sapiens (Human)
Gene	DRD5
Synonym	Gpcr1 DRD1L2 DRD1B dopamine receptor 5 Dopamine D5 receptor D5 receptor D1beta dopamine receptor D(5) dopamine receptor D(1B) dopamine receptor [ Show all ]
Disease	Solid tumours Schizophrenia
Length	477
Amino acid sequence	MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
UniProt	P21918
Protein Data Bank	N/A
GPCR-HGmod model	P21918
3D structure model	This predicted structure model is from GPCR-EXP P21918.
BioLiP	N/A
Therapeutic Target Database	T46828
ChEMBL	CHEMBL1850
IUPHAR	218
DrugBank	BE0000145, BE0004889

Ligand

Name	(2s)-2-amino-4-sulfinobutanoic acid
Molecular formula	C4H9NO4S
IUPAC name	(2S)-2-amino-4-sulfinobutanoic acid
Molecular weight	167.179
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.8
Synonyms	Butanoic acid, 2-amino-4-sulfino-, (2S)- L-Homocysteinesulphinic Acid ZINC25720432 CTK4F8661 PDSP1_001272 AKOS030568392 L-homocysteine sulfinic acid PDSP2_001260 Butanoic acid,2-amino-4-sulfino-, (2S)- NCGC00163274-01 AC1L2PR4 FT-0634441 PDSP1_001276 BDBM86201 L-Homocysteinesulfinic acid SCHEMBL10135851 2686-70-6 CHEMBL1516176 NCGC00163274-02 AC1Q5QML FT-0639107 PDSP2_001256 [ Show all ]
Inchi Key	PDNJLMZEGXHSCU-VKHMYHEASA-N
Inchi ID	InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1
PubChem CID	75896
ChEMBL	N/A
IUPHAR	N/A
BindingDB	86201
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID12649361	BindingDB

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