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Name | 5-hydroxytryptamine receptor 2A |
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Species | Bos taurus (Bovine) |
Gene | HTR2A |
Synonym | 5-HT-2 5-HT-2A Serotonin receptor 2A |
Disease | N/A for non-human GPCRs |
Length | 470 |
Amino acid sequence | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV |
UniProt | Q75Z89 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3446 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL298534 |
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Molecular formula | C26H33FN2O7 |
IUPAC name | 4-fluoro-N-[4-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]butyl]benzamide;oxalic acid |
Molecular weight | 504.555 |
Hydrogen bond acceptor | 9 |
Hydrogen bond donor | 3 |
XlogP | None |
Synonyms | N/A |
Inchi Key | PASICOFIPGOEJG-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C24H31FN2O3.C2H2O4/c1-3-14-27(20-16-21-22(29-2)7-6-8-23(21)30-17-20)15-5-4-13-26-24(28)18-9-11-19(25)12-10-18;3-1(4)2(5)6/h6-12,20H,3-5,13-17H2,1-2H3,(H,26,28);(H,3,4)(H,5,6) |
PubChem CID | 44296014 |
ChEMBL | CHEMBL298534 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 3000.0 nM | PMID7912735 | ChEMBL |
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