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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Substance-P receptor
Species	Cavia porcellus (Guinea pig)
Gene	TACR1
Synonym	NK-1 receptor NK-1R SPR Tachykinin receptor 1
Disease	N/A for non-human GPCRs
Length	407
Amino acid sequence	MDNVLPVDSDLFPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPGRVVCMIEWPSHPDKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAADYEGLEMKSTRYFQTQGSVYKVSRLETTISTVVGAHEEDPEEGPKATPSSLDLTSNGSSRSNSKTVTESSSFYSNMLS
UniProt	P30547
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3942
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL83885
Molecular formula	C33H40N4O5
IUPAC name	4-phenyl-1-[2-[3-pyridin-3-yl-1-(3,4,5-trimethoxybenzoyl)pyrrolidin-3-yl]ethyl]piperidine-4-carboxamide
Molecular weight	572.706
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.4
Synonyms	OODXEPDKPLMODS-UHFFFAOYSA-N 4-Phenyl-1-{2-[3-pyridin-3-yl-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl}-piperidine-4-carboxylic acid amide SCHEMBL8350040 1-[2-[3-(pyridin-3-yl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl]-4-phenyl-piperidine-4-carboxylic acid amide BDBM50290301
Inchi Key	OODXEPDKPLMODS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H40N4O5/c1-40-27-20-24(21-28(41-2)29(27)42-3)30(38)37-19-12-32(23-37,26-10-7-15-35-22-26)11-16-36-17-13-33(14-18-36,31(34)39)25-8-5-4-6-9-25/h4-10,15,20-22H,11-14,16-19,23H2,1-3H3,(H2,34,39)
PubChem CID	44319341
ChEMBL	CHEMBL83885
IUPHAR	N/A
BindingDB	50290301
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	567.0 nM	, Bioorg. Med. Chem. Lett., (1997) 7:19:2531	BindingDB,ChEMBL

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