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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Cysteinyl leukotriene receptor 1
Species	Homo sapiens (Human)
Gene	CYSLTR1
Synonym	LTD4 receptor LTD4 leukotriene D4 receptor HMTMF81 HG55 G-protein coupled receptor HG55 CysLT1 receptor Cysteinyl leukotriene D4 receptor CysLTR1 CYSLT1R [ Show all ]
Disease	N/A
Length	337
Amino acid sequence	MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
UniProt	Q9Y271
Protein Data Bank	N/A
GPCR-HGmod model	Q9Y271
3D structure model	This predicted structure model is from GPCR-EXP Q9Y271.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1798
IUPHAR	269
DrugBank	BE0000705

Ligand

Name	CHEMBL1213844
Molecular formula	C22H14O5
IUPAC name	4-oxo-2-(4-phenoxyphenyl)chromene-8-carboxylic acid
Molecular weight	358.349
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	4-oxo-2-(4-phenoxyphenyl)-4H-chromene-8-carboxylic acid BDBM50323889
Inchi Key	BIMVSKOKCKSLBJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H14O5/c23-19-13-20(27-21-17(19)7-4-8-18(21)22(24)25)14-9-11-16(12-10-14)26-15-5-2-1-3-6-15/h1-13H,(H,24,25)
PubChem CID	49863641
ChEMBL	CHEMBL1213844
IUPHAR	N/A
BindingDB	50323889
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	55000.0 nM	PMID20621485	BindingDB,ChEMBL

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