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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin F2-alpha receptor
Species	Mus musculus (Mouse)
Gene	Ptgfr
Synonym	prostaglandin F2-alpha receptor prostaglandin F receptor (FP) prostaglandin F receptor PGF2-alpha receptor PGF2 alpha receptor PGF receptor PF2AR FP receptor Prostanoid FP receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	366
Amino acid sequence	MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL
UniProt	P43117
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5000
IUPHAR	344
DrugBank	N/A

Ligand

Name	CHEMBL20324
Molecular formula	C29H30O5
IUPAC name	3-[3-oxo-5,6-bis(phenylmethoxy)-2-propyl-1H-inden-2-yl]propanoic acid
Molecular weight	458.554
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.7
Synonyms	1H-Indene-2-propanoicacid, 2,3-dihydro-1-oxo-5,6-bis(phenylmethoxy)-2-propyl- CTK2F4558
Inchi Key	NBZBRMBEAWOCAH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H30O5/c1-2-14-29(15-13-27(30)31)18-23-16-25(33-19-21-9-5-3-6-10-21)26(17-24(23)28(29)32)34-20-22-11-7-4-8-12-22/h3-12,16-17H,2,13-15,18-20H2,1H3,(H,30,31)
PubChem CID	9933857
ChEMBL	CHEMBL20324
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	>20.0 %	PMID423186	ChEMBL
Inhibition	35.0 %	PMID423186	ChEMBL
Inhibition	40.0 %	PMID423186	ChEMBL
Inhibition	50.0 %	PMID423186	ChEMBL
Inhibition	70.0 %	PMID423186	ChEMBL
Inhibition	80.0 %	PMID423186	ChEMBL
Inhibition	90.0 %	PMID423186	ChEMBL

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