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GLASS

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GPCR

Name	Neuropeptide S receptor
Species	Homo sapiens (Human)
Gene	NPSR1
Synonym	G-protein coupled receptor for asthma susceptibility vasopressin receptor-related receptor 1 G protein-coupled receptor 154 PGR14 NPS receptor G-protein coupled receptor 154 GPR154 G-protein coupled receptor PGR14 VRR1 [ Show all ]
Disease	Neurological disease
Length	371
Amino acid sequence	MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI
UniProt	Q6W5P4
Protein Data Bank	N/A
GPCR-HGmod model	Q6W5P4
3D structure model	This predicted structure model is from GPCR-EXP Q6W5P4.
BioLiP	N/A
Therapeutic Target Database	T20958
ChEMBL	CHEMBL5162
IUPHAR	302
DrugBank	BE0000948

Ligand

Name	halothane
Molecular formula	C2HBrClF3
IUPAC name	2-bromo-2-chloro-1,1,1-trifluoroethane
Molecular weight	197.379
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	2.3
Synonyms	1,1-Trifluoro-2-chloro-2-bromoethane GTPL2401 2-bromo-2-chloro-1,1,1-trifluoro-ethane Halothane (JP17/USP/INN) 2979-EP2281813A1 HMS2094K17 2979-EP2316458A1 MFCD00009602 AKOS006227959 NCGC00090868-02 BRN 1736947 NSC760138 CF3CHClBr SR-05000001969-1 DB-043111 Epitope ID:150925 Fluorotane 1-Bromo-1-chloro-2,2,2-trifluoroethane, 99% Halotano 2-Bromo-2-chloro-1,1,1-trifluoroethane, >=99.0% (GC) Halothane [USP:INN:BAN:JAN] 2979-EP2292589A1 I14-44700 2979-EP2316827A1 Narcotane AN-23326 NCGC00258404-01 C07515 Rhodialothan CHEMBL931 Tox21_111033_1 DSSTox_CID_5371 Ethane, 2-bromo-2-chloro-1,1,1-trifluoro-, (+-)- (+-)-2-Bromo-2-chloro-1,1,1-trifluoroethane Freon 123B1 Ftorotan [Russian] 2,2-Trifluoro-1-chloro-1-bromoethane 2979-EP2277848A1 Halothanum [INN-Latin] 2979-EP2314587A1 KB-21112 AC1L1G7T Narkotan BCQZXOMGPXTTIC-UHFFFAOYSA-N NSC-760138 CCG-213438 SCHEMBL25588 D00542 DTXSID4025371 Ethane,2-bromo-2-chloro-1,1,1-trifluoro- 1,1,1-Trifluoro-2-chloro-2-bromoethane 1-bromo-1-chloro-2,2,2-trifluorethane Halan 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE Halothane [Anaesthetics, volatile] 2979-EP2284160A1 HSDB 6753 2979-EP2316825A1 MolPort-001-772-004 Alotano NCGC00090868-03 Bromchlortrifluoraethanum Pharmakon1600-01505434 Chalothane TC-170891 Ethane, 1-bromo-1-chloro-2,2,2-trifluoro- Fluothane FT-0626853 151-67-7 Halotano [INN-Spanish] 2-Bromo-2-chloro-1,1-trifluoroethane Halothane, United States Pharmacopeia (USP) Reference Standard 2979-EP2298735A1 InChI=1/C2HBrClF3/c3-1(4)2(5,6)7/h1H 2979-EP2316828A1 Narcotann ne-spofa Anestan NSC 143490 C2HBrClF3 s4570 CS-4523 Tox21_200850 DSSTox_GSID_25371 Ethane, bromochlorotrifluoro- (.+/-.))-Halothane Ftuorotan 2-Brom-2-chlor-1,1,1-trifluorethan Halothane (JP15/USP/INN) 2979-EP2280006A1 Halsan 2979-EP2316457A1 LS-881 ACMC-1BHQY NCGC00090868-01 BDBM50112212 NSC143490 CCRIS 6244 SR-05000001969 D0D8VE EINECS 205-796-5 Fluktan 1,1-Trifluoro-2-bromo-2-chloroethane 1-Bromo-1-chloro-2,2,2-trifluoroethane Halotan 2-Bromo-2-chloro-1,1,1-trifluoroethane, >=99% Halothane [INN:BAN:JAN] 2979-EP2289510A1 HY-B1010 2979-EP2316826A1 Narcotan Alotano [DCIT] NCGC00090868-05 Bromochlorotrifluoroethane Phthorothanum CHEBI:5615 Tox21_111033 DB01159 Ethane, 2-bromo-2-chloro-1,1,1-trifluoro- Fluothane (TN) Ftorotan 2,2,2-Trifluoro-1-chloro-1-bromoethane Halothan 2979-EP2269610A2 Halothanum 2979-EP2298767A1 J-008834 AB01563314_01 Narcotann NE-spofa [Russian] BCQZXOMGPXTTIC-UHFFFAOYSA- NSC-143490 CAS-151-67-7 SBI-0206928.P001 CTK4C7172 WLN: GYEXFFF DSSTox_RID_77767 Ethane,1,1-trifluoro- 1,1,1-Trifluoro-2-bromo-2-chloroethane [ Show all ]
Inchi Key	BCQZXOMGPXTTIC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H
PubChem CID	3562
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB01159
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
	N/A	N/A	DrugBank

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