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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701935
Molecular formula	C19H24N2O
IUPAC name	N-[(4-ethylphenyl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	296.414
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.4
Synonyms	BDBM129394 SCHEMBL12609925 US8802673, 36
Inchi Key	LYUXEIWGFLVELT-LJQANCHMSA-N
Inchi ID	InChI=1S/C19H24N2O/c1-2-15-3-5-16(6-4-15)13-21-18-9-7-17(8-10-18)19-14-20-11-12-22-19/h3-10,19-21H,2,11-14H2,1H3/t19-/m1/s1
PubChem CID	68325659
ChEMBL	CHEMBL3701935
IUPHAR	N/A
BindingDB	129394
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	163.3 nM	, None	BindingDB,ChEMBL

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