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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	G-protein coupled receptor 55
Species	Homo sapiens (Human)
Gene	GPR55
Synonym	GPR55
Disease	N/A
Length	319
Amino acid sequence	MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
UniProt	Q9Y2T6
Protein Data Bank	N/A
GPCR-HGmod model	Q9Y2T6
3D structure model	This predicted structure model is from GPCR-EXP Q9Y2T6.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075322
IUPHAR	109
DrugBank	BE0005802

Ligand

Name	CHEMBL2392181
Molecular formula	C20H17NO6
IUPAC name	4-oxo-8-[(4-propoxybenzoyl)amino]chromene-2-carboxylic acid
Molecular weight	367.357
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.0
Synonyms	BDBM50436018
Inchi Key	LYGXQSMAAKFUQK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H17NO6/c1-2-10-26-13-8-6-12(7-9-13)19(23)21-15-5-3-4-14-16(22)11-17(20(24)25)27-18(14)15/h3-9,11H,2,10H2,1H3,(H,21,23)(H,24,25)
PubChem CID	71733938
ChEMBL	CHEMBL2392181
IUPHAR	N/A
BindingDB	50436018
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	10.0 %	PMID23713606	ChEMBL
Inhibition	21.0 %	PMID23713606	ChEMBL

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