Detailed GPCR-I-TASSER Statistics for Q9Y2T6

Submitted Sequence

>sp|Q9Y2T6|GPR55_HUMAN
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATS
IYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRF
LAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAK
VFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFL
PVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIR
AHRPSRVQLVLQDTTISRG

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sequence MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
Prediction CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCSSSSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
Conf.Score 9999999999876379899999999999999999999999999999886147888879999999999999999998999999982799803187899999999999999999999999579986352204476602688999999999999998899334778860685889878899999999998868999999999999999999617787642055403999999999999999788999999999998467898269999999999999999999989899898048899999999978870432357676899

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sequence MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
Prediction 8466344440436314400100002301200230232122001000101234446210000000000100000000000000000340313201100112133111100100000031001000100302423333100000000110011001010002444433201131346102100211111312331232012000100110141456656443110000000000000120133102110010023132244041330020011101010130002100000000440142025103431443345444568

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sec.Str
Seq		CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCSSSSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
14mbsA 0.22 0.21 0.91 3.43Download --------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLK----SMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTRSGLHYTCSSHFPYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEEEK---KRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ---------------
24mbsA 0.22 0.21 0.90 4.36Download --------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLK----SMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTREGLHYTCSSHFPYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEEEK---KRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFF----------------
34mbsA 0.22 0.21 0.91 3.72Download --------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLK----SMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTREGLHYTCSSHFPYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEEE---KKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ---------------
44djh 0.24 0.27 0.86 1.51Download ---------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTK----MKTATNIYIFNLALADALVTTTMPFQSTVMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGDVDVIECSLQFPDDDYDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSEKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA-----------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFDFCFP---------------
55t1a 0.21 0.24 0.89 1.18Download --------------VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLK----CLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKQDSVYVCGPYFPRG-WNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRINIYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF----------------
64mbsA 0.22 0.21 0.90 3.44Download ---------CQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLK----SMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTRSGLHYTCSSHFPYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMK---EEEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ---------------
75t1a 0.21 0.24 0.88 1.68Download ----------------QIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLK----CLTDIYLLNLAISDLLFLITLPLWAHSAAEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKQKEVYVCGPYFPR-GWNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRINIYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF----------------
84mbsA 0.23 0.21 0.89 4.17Download --------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLK----SMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFEGL--HYTCSSHFPYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREK-------KRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ---------------
94mbsA 0.22 0.21 0.91 3.72Download --------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLK----SMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFTRSGLHYTCSSHFPYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEEEK---KRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ---------------
105c1mA 0.22 0.24 0.89 4.75Download ----GSHSLPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMK----TATNIYIFNLALADALATSTLPFQSVNYLMGWPFNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTQGSIDCTLTFPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL------ITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF--------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.28 (Read more about C-score)
  • Estimated TM-score = 0.75±0.10
  • Estimated RMSD = 5.7±3.6Å

  • Download Model 2
  • C-score = -0.39

  • Download Model 3
  • C-score = -0.57

  • Download Model 4
  • C-score = -0.44

  • Download Model 5
  • C-score = -2.67


    • [Click on Q9Y2T6_results.tar.bz2 to download the tarball file including all modeling results listed on this page]