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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP4 subtype
Species	Mus musculus (Mouse)
Gene	Ptger4
Synonym	EP2 EP4 receptor PGE receptor EP4 subtype PGE2 receptor EP4 subtype prostanoid EP4 receptor
Disease	N/A for non-human GPCRs
Length	513
Amino acid sequence	MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTSQTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
UniProt	P32240
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2489
IUPHAR	343
DrugBank	N/A

Ligand

Name	CHEMBL1929530
Molecular formula	C20H27NO5S
IUPAC name	4-[2-[(4S)-4-[(E,3S)-3-hydroxy-4-(3-methylphenyl)but-1-enyl]-2-oxo-1,3-oxazolidin-3-yl]ethylsulfanyl]butanoic acid
Molecular weight	393.498
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.4
Synonyms	BDBM50360163 SCHEMBL9881239
Inchi Key	LXIKXYLAOXWTDX-KBSZCIAZSA-N
Inchi ID	InChI=1S/C20H27NO5S/c1-15-4-2-5-16(12-15)13-18(22)8-7-17-14-26-20(25)21(17)9-11-27-10-3-6-19(23)24/h2,4-5,7-8,12,17-18,22H,3,6,9-11,13-14H2,1H3,(H,23,24)/b8-7+/t17-,18+/m0/s1
PubChem CID	10023506
ChEMBL	CHEMBL1929530
IUPHAR	N/A
BindingDB	50360163
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2.5 nM	PMID22204740	BindingDB,ChEMBL

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