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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3701970
Molecular formula	C17H20ClN3O2
IUPAC name	6-chloro-5-ethoxy-N-[4-[(2S)-morpholin-2-yl]phenyl]pyridin-3-amine
Molecular weight	333.816
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.7
Synonyms	US8802673, 71 BDBM129429 SCHEMBL12610108
Inchi Key	LMSQUCVEFRGNAE-MRXNPFEDSA-N
Inchi ID	InChI=1S/C17H20ClN3O2/c1-2-22-15-9-14(10-20-17(15)18)21-13-5-3-12(4-6-13)16-11-19-7-8-23-16/h3-6,9-10,16,19,21H,2,7-8,11H2,1H3/t16-/m1/s1
PubChem CID	86766840
ChEMBL	CHEMBL3701970
IUPHAR	N/A
BindingDB	129429
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	168.0 nM	, None	BindingDB,ChEMBL

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