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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Alpha-2A adrenergic receptor
Species	Bos taurus (Bovine)
Gene	ADRA2A
Synonym	Alpha-2A adrenoceptor Alpha-2A adrenoreceptor Alpha-2AAR Alpha-2D adrenergic receptor
Disease	N/A for non-human GPCRs
Length	452
Amino acid sequence	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSGQPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATAAELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSSEHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
UniProt	Q28838
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4744
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	87394-56-7
Molecular formula	C9H12BrN3
IUPAC name	1-(3-bromopyridin-2-yl)piperazine
Molecular weight	242.12
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.3
Synonyms	ACMC-209qk6 CHEMBL295921 Piperazine, 1-(3-bromo-2-pyridinyl)- 1-(3-Bromo-pyridin-2-yl)-piperazine ANW-38692 DTXSID60535565 V8425 BDBM50027013 KB-30175 AJ-83252 CTK5F8318 SCHEMBL2415357 ZINC26898957 1-(3-Bromopyridin-2-yl)piperazine B-4327 FT-0739728 KYMBSIUPQJYAFF-UHFFFAOYSA-N 1-(3-BROMO(PYRIDIN-2-YL))PIPERAZINE AKOS010630963 DA-17786 TR-027345 3-Bromo-2-piperazinopyridine B67493 I02-3158 [ Show all ]
Inchi Key	KYMBSIUPQJYAFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H12BrN3/c10-8-2-1-3-12-9(8)13-6-4-11-5-7-13/h1-3,11H,4-7H2
PubChem CID	13298529
ChEMBL	CHEMBL295921
IUPHAR	N/A
BindingDB	50027013
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	11.0 nM	PMID6139479	BindingDB,ChEMBL

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