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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	4-[(3-bromobenzyl)amino]benzoic acid
Molecular formula	C14H12BrNO2
IUPAC name	4-[(3-bromophenyl)methylamino]benzoic acid
Molecular weight	306.159
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.6
Synonyms	HMS2578B24 STK195073 AN-465/41988529 MolPort-001-593-881 CHEMBL1509579 SR-01000114856 AC1LH8OK MCULE-5802649810 ZINC359867 BDBM62100 SCHEMBL11253864 4-[(3-bromophenyl)methylamino]benzoic acid cid_834064 SR-01000114856-1 AKOS001696148 MLS000698553 SMR000231541 [ Show all ]
Inchi Key	AXQVARVJGFLCSX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H12BrNO2/c15-12-3-1-2-10(8-12)9-16-13-6-4-11(5-7-13)14(17)18/h1-8,16H,9H2,(H,17,18)
PubChem CID	834064
ChEMBL	CHEMBL1509579
IUPHAR	N/A
BindingDB	62100
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<43807.0 nM	PubChem BioAssay data set	ChEMBL
IC50	43807.0 nM	N/A	BindingDB

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